Chambers and Valves of the Heart
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Human heart has four chambers:
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Two upper thin-walled atria – receive blood from body/lungs.
- Two lower thick-walled ventricles – pump blood to lungs/body.
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Septa:
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Atrioventricular septum – separates atria from ventricles.
- Interatrial septum – separates left and right atria.
- Interventricular septum – separates left and right ventricles; much thicker than interatrial septum.
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Atrioventricular valves (between atria and ventricles):
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Tricuspid valve – right atrium → right ventricle (3 cusps).
- Bicuspid/Mitral valve – left atrium → left ventricle (2 cusps).
- Function: Prevent backflow into atria during ventricular contraction.
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Semilunar valves (at exit of ventricles):
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Pulmonary valve – right ventricle → pulmonary artery.
- Aortic valve – left ventricle → aorta.
- Function: Prevent backflow from arteries into ventricles during relaxation.
Circulation of Blood through Heart
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Heart acts as a double pump:
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Pulmonary circulation – blood to lungs.
- Systemic circulation – blood to all body organs (except lungs).
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Right atrium receives deoxygenated blood via:
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Superior vena cava
- Inferior vena cava
- Blood → tricuspid valve → right ventricle → pulmonary valve → pulmonary trunk → pulmonary arteries → lungs.
- Oxygenated blood from lungs → pulmonary veins → left atrium → bicuspid valve → left ventricle → aorta → body.
- Left ventricle wall is about 3x thicker than right ventricle → needs more force to pump blood to entire body.
Cardiac Cycle (Heartbeat)
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Heart works in continuous cycles:
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Chambers relax → filled with blood (diastole).
- Chambers contract → pump blood (systole).
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Diastole:
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Duration: ~0.4 s
- Both atria & ventricles relaxed → filling with blood.
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Atrial systole:
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Duration: ~0.1 s
- Atria contract → push blood into relaxed ventricles.
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Ventricular systole:
- Duration: ~0.3 s
- Ventricles contract → blood pumped to pulmonary artery & aorta.
- Tricuspid & bicuspid valves close; pulmonary & aortic valves open.
- Total one heartbeat: ~0.8 s
- In a lifetime, heart beats ~2.5 billion times.
Sounds of Heartbeat
- “Lubb” – closing of tricuspid & bicuspid valves during ventricular contraction.
- “Dubb” – closing of pulmonary & aortic valves during ventricular relaxation.
- Can be heard with a stethoscope.
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Heart murmurs:
- Caused by valves not closing fully or opening narrowly → turbulent blood flow → hiss sound.
- Serious cases can be treated by valve replacement (artificial or donor).
Human Heart – MCQs with Answers
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How many chambers does the human heart have?
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A) 2
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B) 3
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C) 4 ✅
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D) 5
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Which chambers of the heart are thin-walled?
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A) Ventricles
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B) Atria ✅
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C) Both
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D) None
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Which septum separates the left and right atria?
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A) Interventricular septum
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B) Atrioventricular septum
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C) Interatrial septum ✅
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D) Pericardial septum
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Which septum is thicker?
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A) Interatrial
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B) Interventricular ✅
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C) Atrioventricular
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D) None
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What is the valve between right atrium and right ventricle called?
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A) Bicuspid
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B) Tricuspid ✅
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C) Pulmonary
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D) Aortic
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The bicuspid valve is also known as:
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A) Tricuspid
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B) Mitral ✅
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C) Pulmonary
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D) Aortic
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Which valves open when ventricles contract?
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A) Tricuspid and Bicuspid
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B) Pulmonary and Aortic ✅
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C) All valves
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D) None
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Which valves close during ventricular systole?
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A) Pulmonary and Aortic
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B) Tricuspid and Bicuspid ✅
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C) All valves
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D) None
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The right atrium receives blood via:
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A) Pulmonary veins
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B) Superior and inferior vena cava ✅
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C) Aorta
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D) Pulmonary artery
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Deoxygenated blood leaves the right ventricle through which vessel?
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A) Pulmonary trunk ✅
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B) Aorta
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C) Pulmonary veins
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D) Superior vena cava
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Oxygenated blood returns to the heart via:
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A) Pulmonary arteries
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B) Pulmonary veins ✅
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C) Aorta
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D) Inferior vena cava
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Left ventricle wall is thicker than the right because:
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A) Pumps blood to lungs
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B) Pumps blood to whole body ✅
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C) It has more valves
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D) None of the above
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What is the name of the phase when heart chambers are relaxed?
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A) Systole
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B) Diastole ✅
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C) Cardiac cycle
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D) Pulse
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During which phase do atria contract?
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A) Atrial diastole
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B) Atrial systole ✅
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C) Ventricular systole
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D) Ventricular diastole
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Ventricles contract during:
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A) Atrial systole
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B) Ventricular systole ✅
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C) Diastole
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D) Cardiac pause
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Duration of one heartbeat is approximately:
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A) 0.5 sec
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B) 0.8 sec ✅
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C) 1.0 sec
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D) 1.2 sec
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“Lubb” sound of the heart is caused by:
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A) Closing of semilunar valves
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B) Closing of AV valves ✅
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C) Opening of AV valves
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D) Opening of semilunar valves
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“Dubb” sound of the heart is caused by:
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A) Closing of semilunar valves ✅
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B) Closing of AV valves
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C) Opening of AV valves
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D) Opening of semilunar valves
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Blood from the left ventricle is pumped into:
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A) Pulmonary artery
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B) Aorta ✅
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C) Superior vena cava
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D) Pulmonary vein
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Blood from the right ventricle is pumped into:
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A) Pulmonary artery ✅
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B) Aorta
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C) Superior vena cava
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D) Pulmonary vein
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Heart murmur is caused by:
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A) Complete valve closure
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B) Valve defects causing turbulent blood flow ✅
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C) Healthy blood flow
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D) Thick myocardium
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Which ventricle has a thicker wall?
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A) Right
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B) Left ✅
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C) Both equal
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D) None
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Pulmonary circulation carries blood to:
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A) Lungs ✅
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B) Body
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C) Brain only
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D) Heart
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Systemic circulation carries blood to:
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A) Lungs
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B) Whole body except lungs ✅
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C) Heart only
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D) None
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The lifetime heartbeats of an average person are approximately:
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A) 1 billion
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B) 2.5 billion ✅
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C) 5 billion
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D) 10 billion
Human Heart – Exam-Based Short Q&A
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Q: How many chambers are present in the human heart?
A: The human heart has 4 chambers: 2 atria (upper) and 2 ventricles (lower). -
Q: Which chambers are thin-walled and why?
A: Atria are thin-walled because they only receive blood from veins and do not pump it with high pressure. -
Q: Which septum separates the atria?
A: Interatrial septum separates the left and right atria. -
Q: Which septum separates the ventricles and why is it thicker?
A: Interventricular septum separates the left and right ventricles; it is thicker because the left ventricle pumps blood to the whole body. -
Q: Name the valve between right atrium and right ventricle.
A: Tricuspid valve; it prevents backflow of blood into the right atrium during ventricular contraction. -
Q: What is the bicuspid valve and its function?
A: Also called mitral valve, it is between left atrium and left ventricle, preventing backflow of oxygenated blood into the atrium. -
Q: When do the semilunar valves open?
A: Pulmonary and aortic valves open during ventricular systole to allow blood to flow into arteries. -
Q: When do the atrioventricular valves close?
A: Tricuspid and bicuspid valves close during ventricular contraction to prevent backflow into atria. -
Q: How does deoxygenated blood enter the right atrium?
A: Through superior and inferior vena cava from the body. -
Q: Where does the right ventricle pump blood?
A: Into the pulmonary trunk, which carries blood to the lungs for oxygenation. -
Q: How does oxygenated blood return to the heart?
A: Pulmonary veins carry oxygen-rich blood from the lungs to the left atrium. -
Q: Why is the left ventricle wall thicker than the right?
A: Because it must generate higher pressure to pump blood throughout the entire body. -
Q: What is diastole?
A: Diastole is the relaxation phase when chambers fill with blood. -
Q: What is atrial systole?
A: Contraction of atria to push blood into the ventricles. -
Q: What is ventricular systole?
A: Contraction of ventricles to pump blood into the pulmonary artery and aorta. -
Q: Approximate duration of one complete heartbeat?
A: About 0.8 seconds: diastole 0.4 s, atrial systole 0.1 s, ventricular systole 0.3 s. -
Q: Which valves cause the “Lubb” heart sound?
A: Closing of tricuspid and bicuspid (AV) valves during ventricular contraction. -
Q: Which valves cause the “Dubb” heart sound?
A: Closing of pulmonary and aortic (semilunar) valves during ventricular relaxation. -
Q: Where does blood from left ventricle go?
A: Into the aorta to supply oxygenated blood to the entire body. -
Q: Where does blood from right ventricle go?
A: Into the pulmonary artery to reach the lungs. -
Q: What is a heart murmur and its cause?
A: A heart murmur is an abnormal hiss caused by incomplete or narrow valve closure, creating turbulent blood flow. -
Q: What is the main difference between left and right ventricles?
A: Left ventricle has a thicker wall and pumps blood to whole body; right ventricle pumps blood to lungs. -
Q: What is pulmonary circulation?
A: It carries deoxygenated blood from right ventricle to lungs and returns oxygenated blood to left atrium. -
Q: What is systemic circulation?
A: It carries oxygenated blood from left ventricle to all body parts except lungs, and returns deoxygenated blood to right atrium. -
Q: Approximate number of heartbeats in an average human lifetime?
A: Around 2.5 billion beats.
Human Heart – Long Questions (Exam-Oriented)
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Describe the structure of the human heart including its chambers, wall, and pericardium.
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Explain the differences between atria and ventricles in terms of structure and function.
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Draw a labeled diagram of the human heart and explain the function of each part.
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Explain the structure and function of the atrioventricular valves.
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Explain the structure and function of the semilunar valves.
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Describe the circulation of blood through the heart including pulmonary and systemic circulation.
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Explain why the wall of the left ventricle is thicker than that of the right ventricle.
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Define cardiac cycle and describe its phases including diastole, atrial systole, and ventricular systole with duration.
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Explain the sounds of the heartbeat and how they are produced.
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What are heart murmurs? Describe their causes and possible remedies.
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Describe the differences between pulmonary circulation and systemic circulation.
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Explain how the heart functions as a double pump to maintain oxygenated and deoxygenated blood separation.
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Describe the role of superior and inferior vena cava, pulmonary artery, pulmonary veins, and aorta in blood circulation.
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Discuss the mechanism that prevents backflow of blood in the heart.
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Explain the importance of the cardiac cycle in maintaining continuous blood circulation.
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How does the structure of the heart relate to its function in pumping blood efficiently throughout the body?
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Explain how the human heart adapts to the demands of exercise and increased oxygen requirement.
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Describe the conduction system of the heart (SA node, AV node, bundle of His, Purkinje fibers) and its role in maintaining heart rhythm.
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Explain the difference between atrial and ventricular systole in terms of pressure changes and valve movements.
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Describe the clinical significance of heart sounds and murmurs in diagnosing heart diseases.
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