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Cells: The Basic Unit of Life

The Cell

Cells are the basic unit of life in all living organisms.

Unicellular organisms (e.g., Amoeba, Bacteria): A single cell performs all life functions.

Multicellular organisms (e.g., Plants, Animals): Composed of specialized cells working together.

Seven Basic Properties of Life

Movement

Sperm cells move with flagella.

White blood cells move through the bloodstream.

Organelles also move within cells.

Nutrition

Cells obtain nutrients to produce energy, build structures, and run biochemical reactions.

Respiration

Cells break down glucose to release ATP, the energy currency of the cell.

Excretion

Waste products are removed by diffusion and active transport to prevent toxicity.

Homeostasis

Cells maintain a stable internal environment by controlling the movement of substances across membranes.

Growth

Cells grow by absorbing nutrients and converting them into cellular components.

Reproduction

Mitosis: Produces identical daughter cells for growth and repair.

Meiosis: Produces gametes (sperm and eggs) for sexual reproduction.


3.2 – Cell Theory

Early Discoveries

1665 – Robert Hooke

Observed cork under microscope.

Discovered “little boxes” and named them cellulae (cells).

1673 – Anton van Leeuwenhoek

Improved microscope and observed living cells in pond water ("animalcules").

1809 – Jean Baptiste de-Lamarck

Observed cells in animals and plants.

1831 – Robert Brown

Discovered the nucleus.

1838 – Matthias Schleiden

Concluded all plants are made of cells.

1839 – Theodor Schwann

Concluded all animals are made of cells.

1855 – Rudolf Virchow

Proposed “All cells come from pre-existing cells.”

1862 – Louis Pasteur

Experimentally proved Virchow’s idea.


Three Points of Cell Theory

All living organisms are composed of one or more cells.

The cell is the basic unit of structure and function in organisms.

All cells come from the division of pre-existing cells.


Validation of Cell Theory

Microscopy: Light and electron microscopes show cells are structural units of life.

Cell Imaging & Genetics: Track cell replication → confirm new cells arise from existing cells.

DNA Studies: Show cells share genetic material and metabolic pathways.

Cell Culture & Tissue Engineering: Show cell growth, division, and differentiation.


Exceptions to Cell Theory

Viruses, Prions, Viroids

Not made of cells.

Cannot reproduce independently → need host cell.

Mitochondria & Chloroplasts

Have their own DNA and can replicate independently.

Suggest endosymbiotic origin.

Multinucleated Structures

Certain fungi and algae have many nuclei in shared cytoplasm.

Muscle Cells (Myocytes)

Can fuse to form multinucleated fibers, challenging the concept of a single-cell unit.

Comparison: Cell Theory vs Exceptions

Aspect

Cell Theory (General Rule)

Exceptions / Special Cases

Living organisms

All living things are made up of one or more cells.

Viruses, prions, and viroids are not made of cells but show some life-like properties.

Basic unit of life

Cell is the basic structural and functional unit of life.

Multinucleated organisms (some fungi, algae) and muscle fibers challenge this concept.

Origin of cells

All cells come from pre-existing cells (Virchow’s principle).

Viruses do not arise from cells but need a host cell for reproduction.

Organelles

Organelles function under the control of the nucleus.

Mitochondria and chloroplasts have their own DNA and replicate independently (endosymbiotic theory).

Cell boundaries

Each cell is usually a separate compartment with its own membrane.

Syncytial structures (shared cytoplasm with multiple nuclei) blur the concept of individual cells.

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